KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SRPK1
All Species:
13.64
Human Site:
S399
Identified Species:
25
UniProt:
Q96SB4
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96SB4
NP_003128.3
655
74325
S399
N
Q
E
S
S
F
L
S
S
Q
N
G
D
S
S
Chimpanzee
Pan troglodytes
XP_518428
831
92792
S575
N
Q
E
S
S
F
L
S
S
Q
N
G
D
S
S
Rhesus Macaque
Macaca mulatta
XP_001116721
831
92803
S575
N
Q
E
S
S
F
L
S
S
Q
N
G
D
S
S
Dog
Lupus familis
XP_850330
823
92006
G567
K
Q
E
P
S
F
L
G
S
Q
N
G
D
S
S
Cat
Felis silvestris
Mouse
Mus musculus
O70551
648
73070
N399
K
Q
E
P
S
F
L
N
S
S
N
G
D
S
S
Rat
Rattus norvegicus
NP_001020897
655
73837
S399
K
Q
E
P
S
F
L
S
S
P
N
G
D
S
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516210
528
59280
Q315
E
E
Q
S
F
N
E
Q
E
I
S
Q
L
Q
E
Chicken
Gallus gallus
XP_419265
754
84415
Q500
F
H
S
C
N
Y
S
Q
R
N
G
D
V
E
N
Frog
Xenopus laevis
NP_001085122
605
68633
P374
D
I
D
G
Q
H
I
P
N
A
V
E
V
M
L
Zebra Danio
Brachydanio rerio
NP_001074138
640
71523
Y383
T
S
E
P
T
N
P
Y
P
A
C
N
G
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q03563
1003
112508
K557
G
I
I
H
T
D
I
K
P
E
N
V
L
I
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P51567
427
49548
M214
L
L
E
C
V
A
F
M
H
D
L
R
M
I
H
Baker's Yeast
Sacchar. cerevisiae
Q03656
742
83219
K473
N
N
N
N
D
N
S
K
N
K
N
N
N
N
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
78.5
78.2
76.7
N.A.
91.4
91.4
N.A.
65.5
70.1
67.6
64.7
N.A.
N.A.
N.A.
23.1
N.A.
Protein Similarity:
100
78.6
78.5
77.6
N.A.
94.6
94
N.A.
70.3
77.3
78.1
76.1
N.A.
N.A.
N.A.
37.1
N.A.
P-Site Identity:
100
100
100
80
N.A.
73.3
80
N.A.
6.6
0
0
6.6
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
80
N.A.
80
80
N.A.
26.6
20
26.6
20
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
32.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36
49.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
8
0
0
0
16
0
0
0
0
0
% A
% Cys:
0
0
0
16
0
0
0
0
0
0
8
0
0
0
0
% C
% Asp:
8
0
8
0
8
8
0
0
0
8
0
8
47
0
0
% D
% Glu:
8
8
62
0
0
0
8
0
8
8
0
8
0
8
16
% E
% Phe:
8
0
0
0
8
47
8
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
0
8
0
0
0
8
0
0
8
47
8
0
0
% G
% His:
0
8
0
8
0
8
0
0
8
0
0
0
0
0
8
% H
% Ile:
0
16
8
0
0
0
16
0
0
8
0
0
0
16
0
% I
% Lys:
24
0
0
0
0
0
0
16
0
8
0
0
0
0
0
% K
% Leu:
8
8
0
0
0
0
47
0
0
0
8
0
16
0
8
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
8
0
% M
% Asn:
31
8
8
8
8
24
0
8
16
8
62
16
8
8
16
% N
% Pro:
0
0
0
31
0
0
8
8
16
8
0
0
0
0
0
% P
% Gln:
0
47
8
0
8
0
0
16
0
31
0
8
0
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% R
% Ser:
0
8
8
31
47
0
16
31
47
8
8
0
0
47
47
% S
% Thr:
8
0
0
0
16
0
0
0
0
0
0
0
0
8
8
% T
% Val:
0
0
0
0
8
0
0
0
0
0
8
8
16
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _